Investigating the role of CXCR2 signalling in pancreatic inflammation and cancer

Steele, Colin W. (2014) Investigating the role of CXCR2 signalling in pancreatic inflammation and cancer. PhD thesis, University of Glasgow.

Due to Embargo and/or Third Party Copyright restrictions, this thesis is not available in this service.

Abstract

C-X-C motif receptor 2 (CXCR2) is a G-protein coupled receptor normally expressed on granulocytes, in particular CD11b +, Gr1+, Ly6G+ bone marrow derived suppressor cells (BMDCs) and once differentiated neutrophils.

Item Type: Thesis (PhD)
Qualification Level: Doctoral
Additional Information: Due to copyright restrictions the full text of this thesis cannot be made available online. Access to the printed version is available once any embargo periods have expired.

Appendix: 1 published article. Inhibition of CXCR2 profoundly suppresses inflammation-driven and spontaneous tumorigenesis. Journal of Clinical Investigation. 2012;122(9):3127–3144. : doi:10.1172/JCI61067

Keywords: Pancreatitis, inflammation, cancer.
Subjects: R Medicine > RD Surgery
R Medicine > RM Therapeutics. Pharmacology
Colleges/Schools: College of Medical Veterinary and Life Sciences > Institute of Cancer Sciences
Supervisor's Name: Sansom, Professor Owen J.
Date of Award: 2014
Depositing User: Dr Colin Steele
Unique ID: glathesis:2014-5809
Copyright: Copyright of this thesis is held by the author.
Date Deposited: 21 Jan 2015 08:36
Last Modified: 21 Dec 2017 13:33
URI: http://theses.gla.ac.uk/id/eprint/5809

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