Identifying clusters in Bayesian disease mapping

Anderson, Craig (2015) Identifying clusters in Bayesian disease mapping. PhD thesis, University of Glasgow.

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Abstract

This thesis develops statistical methodology for disease mapping, an increasingly important field of spatial epidemiology. Disease mapping has applications in public health by allowing for identification of areas which are at high risk of particular health problems. Such approaches are generally based on areal data, which involves partitioning the study region into a set of non-overlapping areal units and recording counts of disease cases within each areal unit. The majority of approaches assume a spatially smooth risk surface, but this may not be realistic, and there has been recent interest in developing methodology which allows for discontinuities in this structure. This can be done by identifying clusters of areal units with similar disease risks, and allowing for discontinuities between these clusters. The work presented in this thesis develops models to identify such clusters and also estimate disease risk. Three Bayesian hierarchical models are proposed; the first two are based on spatial data at a single time point, while the third extends into the spatio-temporal domain by modelling across multiple time points. Each model is applied to respiratory hospital admission data from the Greater Glasgow and Clyde Health Board area in order to identify clusters which have high disease risk.

Item Type: Thesis (PhD)
Qualification Level: Doctoral
Keywords: Bayesian, spatial statistics, epidemiology, spatio-temporal modelling
Subjects: H Social Sciences > HA Statistics
R Medicine > RA Public aspects of medicine
Colleges/Schools: College of Science and Engineering > School of Mathematics and Statistics > Statistics
Funder's Name: UNSPECIFIED
Supervisor's Name: Lee, Dr. Duncan and Dean, Dr. Nema
Date of Award: 2015
Depositing User: Mr Craig Anderson
Unique ID: glathesis:2015-6107
Copyright: Copyright of this thesis is held by the author.
Date Deposited: 13 Feb 2015 11:47
Last Modified: 13 Feb 2015 12:33
URI: http://theses.gla.ac.uk/id/eprint/6107

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