The Motor Activity of the Small Intestine and Its Relation to Acetylcholine, with Additional Papers on Action of Urea, Atropine and Eserine on the Small Intestine

Lazarus, Samuel (1937) The Motor Activity of the Small Intestine and Its Relation to Acetylcholine, with Additional Papers on Action of Urea, Atropine and Eserine on the Small Intestine. MD thesis, University of Glasgow.

Abstract

Within recent years considerable interst has centred around the transmission of nerve impulses from nerve endings to effector organs by chemical substances. Among such, acetylcholine, as the chemical mediator of the parasympathetic system has received most attention. Recent work has indicated that in addition to this importnat role acetylcholine plays a part in the regulation of the tine and rhythmicity of the visceral muscle of the gastro-intestinal tract. The present research is an attempt to show that acetylcholine is constantly formed in the tissues of the small intestine; that it exerts a powerfil excito-motor effect on the visceral muscle of the intestine at the site of its formation, and that it is then hydrolysed, by the chorile-esterase, into choline and acetic anhydride. I have also been able to demonstrate that atrophine, eserine and urea influence this acetylcholine mechanism and so alter the motor activity of the bowel.

• Item Type: Thesis (MD)
• Qualification Level: Doctoral
• Keywords: Medicine, Physiology
• Date of Award: 1937
• Depositing User: Enlighten Team
• Unique ID: glathesis:1937-80084
• Copyright: Copyright of this thesis is held by the author.
• Date Deposited: 03 Mar 2020 09:32
• Last Modified: 03 Mar 2020 09:32
• URI: https://theses.gla.ac.uk/id/eprint/80084