Effects of raspberry ketone and green coffee bean extract on body mass and substrate utilisation

Johnston, Lynsey (2019) Effects of raspberry ketone and green coffee bean extract on body mass and substrate utilisation. MSc(R) thesis, University of Glasgow.

Abstract

Dietary food supplements are becoming increasingly popular and while many claim to aid weight loss, there is limited evidence to support such claims. Raspberry ketone and green coffee bean extract have both been marketed for weight loss and are often sold in a combined form. The aim of the present study was to test whether raspberry ketone and green coffee bean extract, when consumed separately and in combination, affect substrate utilisation and body composition. In a single blind randomised control trial, 32 healthy recreationally active males and females (age: 30.4 ± 1.5 years; BMI: 26.7 ± 0.4 kg.m-2; body mass: 79.0 ± 1.8 kg; V̇O2max: 37.7 ± 1.4 ml.kg-1.min-1) were randomly assigned to four different treatment groups for 8 weeks; raspberry ketone (RK) (200 mg/day), green coffee bean extract (CGE) (400 mg/day), raspberry ketone plus green coffee bean extract (RK+CGE) (200 mg/day plus 400 mg/day) or control (200 mg/day). Resting metabolic rate, anthropometry, body composition and metabolic responses during a 30-minute steady state exercise test (55% V̇O2max) were measured at baseline and repeated post intervention. There was no effect of either supplement alone, or in combination on body mass (Baseline vs post intervention - RK: 82.5 ± 3.8 vs 81.6 ± 3.9, CGE: 81.1 ± 3.0 vs 81.0 ± 3.2, RK+CGE: 75.9 ± 3.8 vs 74.5 + 4.0, Control: 76.7 ± 4.1 vs 76.3 ± 4.2kg (p>0.05)) or body fat (Baseline vs post intervention - RK: 25.6 ± 3.3 vs 25.9 ± 2.7, CGE: 28.2 ± 4.3 vs 28.7 ± 4.2, RK+CGE: 33.0 ± 3.8 vs 32.4 ± 3.7, Control 25.8 ± 3.6 vs 25.8 ± 3.3% (p>0.05)). Similarly, no effect on substrate utilisation was observed either at rest (Baseline vs post intervention RER - RK: 0.83 ± 0.02 vs 0.84 ± 0.01, GCE: 0.84 ± 0.02 vs 0.83 ± 0.01, RK+GCE: 0.85 ± 0.03 vs 0.82 ± 0.03, Control: 0.82 ± 0.02 vs 0.84 ± 0.01 (p>0.05)) or during exercise (Baseline vs post intervention RER - RK: 0.89 ± 0.01 vs 0.87 ± 0.02, GCE: 0.90 ± 0.02 vs 0.90 ± 0.01, RK+GCE: 0.85 ± 0.01 vs 0.84 ± 0.01, Control: 0.86 ± 0.02 vs 0.87 ± 0.02 (p>0.05)). In conclusion, this study demonstrated that 8-weeks of supplementation with raspberry ketone, green coffee extract and a combination of these supplements had no effect on body mass, body composition or substrate utilisation.

• Item Type: Thesis (MSc(R))
• Qualification Level: Masters
• Keywords: Raspberry ketone, green coffee bean extract, body mass, substrate utilisation.
• Subjects: Q Science > QP Physiology
• Colleges/Schools: College of Medical Veterinary and Life Sciences > School of Life Sciences
• Supervisor's Name: MacFarlane, Professor Niall and Gray, Dr. Stuart
• Date of Award: 2019
• Depositing User: Miss Lynsey Johnston
• Unique ID: glathesis:2019-75166
• Copyright: Copyright of this thesis is held by the author.
• Date Deposited: 08 Nov 2019 11:14
• Last Modified: 10 Dec 2019 12:10
• Thesis DOI: 10.5525/gla.thesis.75166
• URI: https://theses.gla.ac.uk/id/eprint/75166