Barlog, Maciej L.
Asymmetric synthesis of homoallylic alcohols and their applications.
PhD thesis, University of Glasgow.
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Herein it is presented a further development of the well-established catalytic asymmetric allylation of aldehydes leading to enantiopure homoallylic alcohols
Stereogenic centre(s) served as the foundation for synthesis of a variety of other advanced intermediates and building blocks with multiple chiral centres
- New approaches to homoallylic alcohols were dementrated with excellent control of chiral centers
- Biologically relevant carbohydrate analogues were synthesised in four possible configurations using singlet oxygen raction as the key step
- δ-hydroxy-β-amino acids were synthetised diastereoselectively using Pd catalysis as the key step.
- A novel approach to synthesis of isoxazolidines and pyrazolidines was demonstrated
||Asymmetric synthesis, allylation, Palladium catalysed reactions, Carbonylation, beta amino acids, isoxazolidines.
||Q Science > QD Chemistry
||College of Science and Engineering > School of Chemistry
|| Kočovský, Professor Pavel and Malkov, Professor Andrei V.
|Date of Award:
Mr Maciej Barlog
||Copyright of this thesis is held by the author.
||05 Sep 2011
||15 Oct 2014 09:06
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