Development of novel radiotracers as tools for imaging the human brain

Tavares, Adriana A.S. (2011) Development of novel radiotracers as tools for imaging the human brain. PhD thesis, University of Glasgow.

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Abstract

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n-specific binding observed throughout the brain, a low binding potential (BPND<
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Item Type: Thesis (PhD)
Qualification Level: Doctoral
Keywords: PET and SPECT, translocator protein, noradrenaline transporter, high performance liquid chromatography, brain uptake, lipophilicity, non-specific binding, binding potential, radiotracer discovery and development, radiosynthesis, rats, non-human primates, reboxetine, PK11195, plasma protein binding, permeability, compound-membrane interactions
Subjects: Q Science > QD Chemistry
R Medicine > RZ Other systems of medicine
Colleges/Schools: College of Medical Veterinary and Life Sciences > Institute of Neuroscience and Psychology
Supervisor's Name: Pimlott, Dr. Sally and Dewar, Dr. Deborah
Date of Award: 2011
Depositing User: Miss Adriana A. S. Tavares
Unique ID: glathesis:2011-2919
Copyright: Copyright of this thesis is held by the author.
Date Deposited: 01 Nov 2011
Last Modified: 10 Dec 2012 14:01
URI: http://theses.gla.ac.uk/id/eprint/2919

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