Evoked otoacoustic emissions as alternative tests of auditory function in companion animals

McBrearty, Alix Rebecca (2012) Evoked otoacoustic emissions as alternative tests of auditory function in companion animals. MVM(R) thesis, University of Glasgow.

Due to Embargo and/or Third Party Copyright restrictions, this thesis is not available in this service.

Abstract

A variety of causes of sensorineural deafness, including pigment-associated congenital deafness and presbycusis have been reported in dogs, cats and horses. Deafness is particularly important in these species as it can result in an inability to anticipate hazards which can endanger the animals‟ life and because it can be detrimental to the relationship between the animal and owner. The current preferred method for assessing auditory function in these species is the brainstem auditory evoked response (BAER) test. In humans, evoked otoacoustic emission (EOAE) tests are widely used for hearing screening, detecting partial hearing loss and monitoring cochlear outer hair cell function over time. Two types of EOAE are commonly used clinically: transient evoked OAEs (TEOAEs) and distortion product OAEs (DPOAEs). The aims of these studies were to investigate the feasibility of TEOAE testing in conscious puppies and of TEOAE and DPOAE testing in sedated adolescent and adult dogs presented for hearing screening. The ability of these tests to correctly identify the hearing status of canine ears, as defined by BAER, was also evaluated. In cats and horses, I investigated whether TEOAEs and DPOAEs could be recorded and evaluated the use of human neonatal screening protocols in cats and horses with apparently normal hearing. In these studies I have shown for the first time that EOAE testing can be used in dogs presented for audiological evaluation. I have developed and evaluated protocols for recording EOAEs using a commercially available device. The EOAE tests had a high sensitivity and specificity for diagnosing complete deafness when compared to the BAER test. The EOAE tests were successfully performed in cats and horses for the first time and the protocols used have been described. These studies have added to our knowledge and understanding of EOAEs in companion animals and have demonstrated the potential of these tests as diagnostic tools to assess cochlear function in these species.

Item Type: Thesis (MVM(R))
Qualification Level: Masters
Additional Information: Due to copyright restrictions the full text of this thesis cannot be made available online. Access to the printed version is available once any embargo periods have expired.
Subjects: S Agriculture > SF Animal culture > SF600 Veterinary Medicine
Colleges/Schools: College of Medical Veterinary and Life Sciences > School of Veterinary Medicine
Funder's Name: UNSPECIFIED
Supervisor's Name: Penderis, Prof. Jacques
Date of Award: 2012
Depositing User: Mrs Marie Cairney
Unique ID: glathesis:2012-4187
Copyright: Copyright of this thesis is held by the author.
Date Deposited: 16 Apr 2013 08:11
Last Modified: 16 Apr 2013 08:18
URI: http://theses.gla.ac.uk/id/eprint/4187

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