Neurotransmitter phenotypes of descending systems in the rat lumbar spinal cord

Du Beau, Amy (2013) Neurotransmitter phenotypes of descending systems in the rat lumbar spinal cord. PhD thesis, University of Glasgow.

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Abstract

Sensorimotor processes within the spinal cord are profoundly influenced by descending systems from the brain yet the neurotransmitter phenotypes of these systems remains enigmatic. Using tract tracing methods, this study identifies the neurochemical content of axons descending from the sensorimotor cortex and sites within the anatomically diverse reticular formation. There are several classes of neurons in spinal lumbar segments targeted by these descending systems which contribute to recruiting adaptively appropriate motor patterns. This study investigates the neuronal targets of descending systems and the neurochemical content of their inputs. Immunofluorescent tissue containing labelled neuronal processes were examined and reconstructed interneurons were defined according to their neuronal geometry and morphology across laminar boundaries.

Item Type: Thesis (PhD)
Qualification Level: Doctoral
Keywords: spinal cord, vesicular glutamate transporters, GABA, glycine, serotonin, immunocytochemistry, neurotransmitter, interneuron
Subjects: Q Science > QP Physiology
Colleges/Schools: College of Medical Veterinary and Life Sciences > Institute of Neuroscience and Psychology > Neurosciences and Clinical Psychology
Funder's Name: UNSPECIFIED
Supervisor's Name: Maxwell, Professor David
Date of Award: November 2013
Depositing User: Miss Amy Du Beau
Unique ID: glathesis:2013-4721
Copyright: Copyright of this thesis is held by the author.
Date Deposited: 13 Jan 2014 10:19
Last Modified: 13 Jan 2014 16:51
URI: http://theses.gla.ac.uk/id/eprint/4721

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