The isolation and characterisation of temperature-sensitive mutants of R. S. virus

Faulkner, Georgine Potter (1975) The isolation and characterisation of temperature-sensitive mutants of R. S. virus. PhD thesis, University of Glasgow.

Full text available as:
[img]
Preview
PDF
Download (11MB) | Preview

Abstract

The RSN-2 strain of RS virus grown in BS-C-1 cells was used for the isolation and characterisation of ts mutants. RSN-2 strain growth was examined at different temperatures and the degree of cell-association of the virus calculated. The effect of DM inhibitors such as actinomycin D and mitomycin C as well as the effect of the concentration of phenylalanine, arginine and serum on RS virus was studied. Thin sections of RS virus infected cells were examined by electron microscopy. Infected cells were also examined under a scanning electron microscope. Thirty-five ts mutants of the RSN-2 strain were isolated from mutagenised virus and one ts mutant from non-mutagenised virus. A few ts mutants were ts at 37

Item Type: Thesis (PhD)
Qualification Level: Doctoral
Additional Information: Adviser: C R Pringle
Keywords: Virology
Date of Award: 1975
Depositing User: Enlighten Team
Unique ID: glathesis:1975-74250
Copyright: Copyright of this thesis is held by the author.
Date Deposited: 23 Sep 2019 15:33
Last Modified: 23 Sep 2019 15:33
URI: http://theses.gla.ac.uk/id/eprint/74250

Actions (login required)

View Item View Item

Downloads

Downloads per month over past year