AP-1 Regulates a Multigenic Invasion Programme in v-fos FBR MuSV Transformed Fibroblasts

Johnston, Imogen Michelle Petro (1999) AP-1 Regulates a Multigenic Invasion Programme in v-fos FBR MuSV Transformed Fibroblasts. PhD thesis, University of Glasgow.

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Abstract

The oncogene v-fos, is the transforming agent of the FBJ-MuSV and the FBR-MuSV osteosarcoma virus that elicits cellular responses through activation of the multigenic transcription factor AP-1. The Suppressive Subtractive Hybridisation (SSH), technique has been employed to identify differentially expressed downstream direct and indirect target genes of the AP-1 transcription factor in a rat fibroblast cell system by using FBJ-MuSV v-fos transformed 208F fibroblasts and the normal parental fibroblast 208F cell lines.

Item Type: Thesis (PhD)
Qualification Level: Doctoral
Additional Information: Adviser: J Wyke
Keywords: Genetics, Oncology, Medicine
Date of Award: 1999
Depositing User: Enlighten Team
Unique ID: glathesis:1999-74531
Copyright: Copyright of this thesis is held by the author.
Date Deposited: 27 Sep 2019 17:54
Last Modified: 27 Sep 2019 17:54
URI: http://theses.gla.ac.uk/id/eprint/74531

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