Purification and Characterisation of the Isocitrate Dehydrogenase From Streptomyces coelicolor and Cloning of Its Gene

Taylor, Richard David (1992) Purification and Characterisation of the Isocitrate Dehydrogenase From Streptomyces coelicolor and Cloning of Its Gene. PhD thesis, University of Glasgow.

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Abstract

As part of an effort to increase our understanding of central metabolic pathways in streptomycetes, the TCA cycle enzyme, isocitrate dehydrogenase (IDH), was studied from Streptomyces coelicolor. In Eschericia coli grown on acetate as a sole carbon source, IDH plays an important role in controlling the flux of carbon between the glyoxylate bypass and the TCA cycle. The study of any such control in streptomycetes is of interest because these pathways are important in providing energy and precursors for both primary and secondary metabolism.

Item Type: Thesis (PhD)
Qualification Level: Doctoral
Additional Information: Adviser: Hugh G Nimmo
Keywords: Biochemistry, Genetics
Date of Award: 1992
Depositing User: Enlighten Team
Unique ID: glathesis:1992-74607
Copyright: Copyright of this thesis is held by the author.
Date Deposited: 27 Sep 2019 17:34
Last Modified: 27 Sep 2019 17:34
URI: http://theses.gla.ac.uk/id/eprint/74607

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