The Role of 1,25 Dihydroxyvitamin D3 and Other Calciotrophic Hormones as Immunoregulatory Agents

Smith, John (1992) The Role of 1,25 Dihydroxyvitamin D3 and Other Calciotrophic Hormones as Immunoregulatory Agents. PhD thesis, University of Glasgow.

Abstract

Over the years it has been well documented that there is a connection between the immune system and the endocrine system certainly as far as vitamin D was concerned. The major breakthrough came when vitamin D receptors were demonstrated on various cells whose principal task was to mount an immune response. 1,25 Dihydroxyvitamin D3 (1,25(OH)2D3), the active metabolite of vitamin D, was demonstrated to inhibit cell proliferation and to inhibit interleukin-2 (IL-2) activity (Tsoukas, 1984). In this thesis the roles of 1,25(OH)2D3 and other calciotrophic hormones as immunoregulatory agents are addressed.

• Item Type: Thesis (PhD)
• Qualification Level: Doctoral
• Additional Information: Adviser: A C Kennedy
• Keywords: Medicine, Immunology
• Date of Award: 1992
• Depositing User: Enlighten Team
• Unique ID: glathesis:1992-74615
• Copyright: Copyright of this thesis is held by the author.
• Date Deposited: 27 Sep 2019 17:32
• Last Modified: 27 Sep 2019 17:32
• URI: https://theses.gla.ac.uk/id/eprint/74615