The Control of Ductus Arteriosus Smooth Muscle Contractility: Studies on the Physiological and Pharmacological Properties of the Isolated Fetal Rabbit Ductus Arteriosus

Smith, Gordon C. S (1994) The Control of Ductus Arteriosus Smooth Muscle Contractility: Studies on the Physiological and Pharmacological Properties of the Isolated Fetal Rabbit Ductus Arteriosus. MD thesis, University of Glasgow.

Full text available as:
[img]
Preview
PDF
Download (4MB) | Preview

Abstract

1. This work studied the smooth muscle of the rabbit ductus arteriosus. The ductus is a shunt blood vessel of the fetus which extends between the main pulmonary artery and aorta and closes after birth. 2. This work had the following aims regarding the isolated fetal rabbit ductus arteriosus (a) to characterise the ideal experimental conditions for study of the vessel; (b) to characterise the dilator prostanoid receptors on the vessel; (c) to characterise the effect of prostaglandin E2 (PGE2) on the response of the vessel to noradrenaline; (d) to characterise the effect of indomethacin on the response of the vessel to PGE2 and other vasodilators; (e) to characterise the effect of oxygen tension on both the response of the vessel to the contractile effect of noradrenaline and the relaxant effect of PGE2 and other vasodilators; and, (f) to characterise contractile effects of prostanoids on the vessel. (Abstract shortened by ProQuest.).

Item Type: Thesis (MD)
Qualification Level: Doctoral
Keywords: Medicine, Physiology
Date of Award: 1994
Depositing User: Enlighten Team
Unique ID: glathesis:1994-75572
Copyright: Copyright of this thesis is held by the author.
Date Deposited: 19 Nov 2019 19:24
Last Modified: 19 Nov 2019 19:24
URI: http://theses.gla.ac.uk/id/eprint/75572

Actions (login required)

View Item View Item

Downloads

Downloads per month over past year