The Structure of Mycophenolic Acid and Studies on Alkyl-Oxygen Bond Fission in Phthalides

Logan, William R (1957) The Structure of Mycophenolic Acid and Studies on Alkyl-Oxygen Bond Fission in Phthalides. PhD thesis, University of Glasgow.

Abstract

The constitution of mycophenolic acid, a mould metabolite of P. brevi-compactum, is dlscussed and its structure confirmed as 4-methyl-5-methoxy-6-(5'-carboxy-3'-methylpent-2'-enyl)-7-hydroxyphthalide by the synthesis of 4-methyl-5:7-dimethoxy-6-carboxy-methylphthalide, a degradation product of the monomethyl ether of the acid and by infrared spectroscopy of the acid and its methyl ether.

• Item Type: Thesis (PhD)
• Qualification Level: Doctoral
• Keywords: Organic chemistry
• Date of Award: 1957
• Depositing User: Enlighten Team
• Unique ID: glathesis:1957-79244
• Copyright: Copyright of this thesis is held by the author.
• Date Deposited: 05 Mar 2020 11:25
• Last Modified: 05 Mar 2020 11:25
• URI: https://theses.gla.ac.uk/id/eprint/79244