Integrated genome sequencing and gene expression analysis in the Stroke-Prone Spontaneously Hypertensive Rat

Dashti, Mohammed (2014) Integrated genome sequencing and gene expression analysis in the Stroke-Prone Spontaneously Hypertensive Rat. PhD thesis, University of Glasgow.

Abstract

This research project attempts to identify the genetic determinants of SHRSP/Gla phenotypes by using mRNA and micro(mi)RNA expression profiling data, in combination with the genome sequence of the SHRSP/Gla and WKY/Gla, to facilitate human translational studies for hypertension and vice versa.

• Item Type: Thesis (PhD)
• Qualification Level: Doctoral
• Keywords: Whole genome sequencing, NGS, microarray, bioinformatics, gene expression analysis, genetics, hypertension, stroke, heart failure, left ventricular hypertrophy, Stroke-Prone Spontaneously Hypertensive Rat, SHRSP, GWAS, miRNA
• Subjects: Q Science > QH Natural history > QH426 Genetics
• Colleges/Schools: College of Medical Veterinary and Life Sciences > School of Cardiovascular & Metabolic Health
• Supervisor's Name: McBride, Dr. Martin and McClure, Dr. John
• Date of Award: 2014
• Depositing User: Mr Mohammed Dashti
• Unique ID: glathesis:2014-6106
• Copyright: Copyright of this thesis is held by the author.
• Date Deposited: 05 Mar 2015 11:42
• Last Modified: 16 Mar 2015 14:52
• URI: https://theses.gla.ac.uk/id/eprint/6106