Immune responses of mice to pulmonary infection with Bordetella pertussis

Stevenson, Lydia Queen (1983) Immune responses of mice to pulmonary infection with Bordetella pertussis. PhD thesis, University of Glasgow.

Abstract

The object of this investigation was to define the nature of the immune responses of mice that had been given a sublethal pulmonary infection with Bordetella pertussis - an infection which shares many features with whooping cough in man. Both serum antibodies and local, secretory antibodies were studied the latter being sampled as tracheobronchial washings (TBW). A particular focus of interest was in those responses that were directed against biologically active components of B. pertussis and in those responses involved in passive protective activity against intracerebral and sublethal intranasal challenge with live B. pertussis. (Abstract shortened by ProQuest.).

• Item Type: Thesis (PhD)
• Qualification Level: Doctoral
• Additional Information: Adviser: A C Wardlaw
• Subjects: Q Science > QR Microbiology > QR180 Immunology
• Colleges/Schools: College of Medical Veterinary and Life Sciences
• Date of Award: 1983
• Depositing User: Enlighten Team
• Unique ID: glathesis:1983-71627
• Copyright: Copyright of this thesis is held by the author.
• Date Deposited: 10 May 2019 14:03
• Last Modified: 07 Nov 2022 11:37
• Thesis DOI: 10.5525/gla.thesis.71627
• URI: https://theses.gla.ac.uk/id/eprint/71627