Studies on the epidemiology and prevention of rubella

Reid, Daniel (1969) Studies on the epidemiology and prevention of rubella. MD thesis, University of Glasgow.

Abstract

The aims of the studies undertaken were as follows: 1. To assess the proportion of women of child-bearing age resident in different regions of the United Kingdom who possess antibody to rubella with special reference to their age-group, country of origin previous history of rubella and obstetric experience. 2, To observe the differences in rubella antibody titre of the various batches of immunoglobulin which are in current use in the United Kingdom and to determine, by means of a controlled trial, the protective effect of immunoglobulin of high rubella antibody titre when given to contacts of rubella who are within the first sixteen weeks of pregnancy. 3. To investigate the infectiousness of the rubella virus in the home, in a semi-residential community and on casual contact with patients suffering from the disease. In addition the proportion of subclinical and second attacks of rubella that can be verified by laboratory means were noted. Although several investigations are described in the thesis each is intended to provide some information on the risk of infection to persons, especially if in early pregnancy, when they are exposed to the rubella virus and to determine the protection they may expect if given immunoglobulin after contact with the disease. Because it Is now possible to isolate the rubella virus and perform antibody titrations the results of each study was based on laboratory findings.

• Item Type: Thesis (MD)
• Qualification Level: Doctoral
• Additional Information: Adviser: T M Pollock
• Keywords: Epidemiology, Immunology
• Date of Award: 1969
• Depositing User: Enlighten Team
• Unique ID: glathesis:1969-73707
• Copyright: Copyright of this thesis is held by the author.
• Date Deposited: 14 Jun 2019 08:56
• Last Modified: 14 Jun 2019 08:56
• URI: https://theses.gla.ac.uk/id/eprint/73707