The effect of oxygen at elevated atmospheric pressure and hypothermia on tissue metabolism

Norman, John Nelson (1964) The effect of oxygen at elevated atmospheric pressure and hypothermia on tissue metabolism. PhD thesis, University of Glasgow.

Abstract

The therapeutic potentialities of hyperbaric oxygen have been intensively investigated in Amsterdam and Glasgow during the past decade but scientists have been interested in the biological properties of high pressures of air or oxygen since the discovery of the phenomenon of atmospheric pressure. The use of hyperbaric oxygen can be classified into three main categories and examples of these form the three principal section of this thesis: 1. The use of hyperbaric oxygen in anoxic states, such as carbon monoxide poisoning, where tissue oxygenation is maintained at adequate levels until the normal method of oxygen transport is restored. 2. The use of the metabolic effects of hyperbaric oxygen on normal tissues to reduce their oxygen consumption and thus prolong the period during which the circulation may be totally arrested as an aid to hear or brain surgery. 3. The toxic effects of hyperbaric oxygen, which may be of use as selective toxic agents against malignant tumour cells or pathogenic bacteria.

• Item Type: Thesis (PhD)
• Qualification Level: Doctoral
• Additional Information: Adviser: Charles FW Illingworth
• Keywords: Pharmacology
• Date of Award: 1964
• Depositing User: Enlighten Team
• Unique ID: glathesis:1964-73756
• Copyright: Copyright of this thesis is held by the author.
• Date Deposited: 14 Jun 2019 08:56
• Last Modified: 14 Jun 2019 08:56
• URI: https://theses.gla.ac.uk/id/eprint/73756