Muscle biopsy analysis of the body water and electrolyte content in health and disease

Graham, John Alistair (1971) Muscle biopsy analysis of the body water and electrolyte content in health and disease. MD thesis, University of Glasgow.

Abstract

The work presented in this thesis describes the measurement of body water and electrolyte contents by analysis of muscle biopsy-specimens. Biopsy-specimens were taken from skeletal muscle (usually vastus lateralis) under either local or general anaesthesia. Each biopsy-specimen is divided into three portions, which are weighed, dried and then weighed again. The total water content is thus obtained, and the total biopsy-specimen sodium, potassium and chloride content are then measured in an acid extract of the tissue. The total water and electrolyte contents are partitioned into extra- and intracellular phases using the chloride content of the biopsy-specimen (corrected for the intracellular content) as an indicator of the extracellular water. (Abstract shortened by ProQuest.).

• Item Type: Thesis (MD)
• Qualification Level: Doctoral
• Additional Information: Adviser: J F Lamb
• Keywords: Medicine
• Date of Award: 1971
• Depositing User: Enlighten Team
• Unique ID: glathesis:1971-74151
• Copyright: Copyright of this thesis is held by the author.
• Date Deposited: 23 Sep 2019 15:33
• Last Modified: 23 Sep 2019 15:33
• URI: https://theses.gla.ac.uk/id/eprint/74151