Effects of Antiepileptic Drugs in Rodent and Human Astrocyte Cultures, Rodent Brain and Pentylenetetrazol-Induced Seizures in Mice

Fraser, Caroline Margaret (1999) Effects of Antiepileptic Drugs in Rodent and Human Astrocyte Cultures, Rodent Brain and Pentylenetetrazol-Induced Seizures in Mice. PhD thesis, University of Glasgow.

Abstract

There is increasing evidence to suggest that most antiepileptic drugs (AEDs) have multiple mechanisms of action which may contribute to their efficacy and/or toxicity. Of particular current interest is the effects of AEDs on the excitatory and inhibitory amino acid systems regulated by glutamate and ?-aminobutyric acid (GABA), respectively.

• Item Type: Thesis (PhD)
• Qualification Level: Doctoral
• Additional Information: Adviser: M J Brodie
• Keywords: Pharmacology
• Date of Award: 1999
• Depositing User: Enlighten Team
• Unique ID: glathesis:1999-74529
• Copyright: Copyright of this thesis is held by the author.
• Date Deposited: 27 Sep 2019 17:55
• Last Modified: 27 Sep 2019 17:55
• URI: https://theses.gla.ac.uk/id/eprint/74529