Characterisation of the Major Merozoite Polypeptides of Theileria annulata

Dickson, Joanne (1993) Characterisation of the Major Merozoite Polypeptides of Theileria annulata. PhD thesis, University of Glasgow.

Abstract

Much of the pathogenicity of the bovine disease tropical theileriosis, caused by the protozoan parasite Theileria annulata, results from the invasion of host erythrocytes by the merozoite stage of the parasite. The aim of this study was, primarily, to investigate the expression of immunodominant, and potentially protective, antigens of Tannulata merozoites. Furthermore, it was intended to characterise the antigenicity and biochemical nature of a previously identified 30 kDa merozoite surface polypeptide, to clone the gene encoding this protein, and to develop an in vitro merozoite invasion assay in order to analyse the process of invasion in detail, particularly with respect to the role of identified merozoite surface proteins. Theileria annulata macroschizont-infected cell lines can be induced to produce merozoites by culture at an elevated temperature (41

• Item Type: Thesis (PhD)
• Qualification Level: Doctoral
• Additional Information: Adviser: Brian Shiels
• Keywords: Parasitology, Animal diseases
• Date of Award: 1993
• Depositing User: Enlighten Team
• Unique ID: glathesis:1993-75287
• Copyright: Copyright of this thesis is held by the author.
• Date Deposited: 19 Nov 2019 21:20
• Last Modified: 19 Nov 2019 21:20
• URI: https://theses.gla.ac.uk/id/eprint/75287