Small Bowel Motility in Ulcerative Colitics Undergoing Ileal Pouch-Anal Anastomosis

McCourtney, James S (1998) Small Bowel Motility in Ulcerative Colitics Undergoing Ileal Pouch-Anal Anastomosis. MD thesis, University of Glasgow.

Abstract

Although much clinical research has been carried out in the last 14 years to examine the postoperative function of patients undergoing ileal pouch-anal anastomosis (IPAA), little is known about the small bowel which is used to create the reservoir in this procedure. This thesis has therefore examined the preoperative small bowel motility characteristics of patients with ulcerative colitis (UC) undergoing EPAA using in vivo and in vitro techniques. The in vitro studies were compared against control subjects of whom most were undergoing elective right hemicolectomy for non-obstructing neoplasms. During part of the research project access to ileal tissue from patients with idiopathic slow transit constipation (ISTC) undergoing subtotal colectomy and ileorectal anastomosis (SC+IRA) enabled a study of this interesting subgroup of patients to be made. A review of the IPAA operation performed at Glasgow Royal Infirmary between 1988 and 1995 i.e. totally stapled restorative proctocolectomy (TSRP), was also carried out. (Abstract shortened by ProQuest.).

• Item Type: Thesis (MD)
• Qualification Level: Doctoral
• Additional Information: Adviser: T G Cooke
• Keywords: Medicine, Surgery
• Date of Award: 1998
• Depositing User: Enlighten Team
• Unique ID: glathesis:1998-75925
• Copyright: Copyright of this thesis is held by the author.
• Date Deposited: 19 Dec 2019 09:15
• Last Modified: 19 Dec 2019 09:15
• URI: https://theses.gla.ac.uk/id/eprint/75925