The Cellular Response to Glucocorticoids in Human Astrocytoma

MacKie, Alison E (1989) The Cellular Response to Glucocorticoids in Human Astrocytoma. MSc(R) thesis, University of Glasgow.

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Glucocorticoids have been widely used in reducing the oedema associated with brain tumours and post-operative pain. In vitro, they have been shown to inhibit growth of several different cell types, for example lung tumours and gliomas. Glucocorticoids have also been found to encourage immature malignant glioma cells to differentiate. This was measured by a reduction in immature properties, such as plasminogen activator activity, and the appearance of differentiated characteristics, such as glutamine synthetase activity.

Item Type: Thesis (MSc(R))
Qualification Level: Masters
Keywords: Medicine
Date of Award: 1989
Depositing User: Enlighten Team
Unique ID: glathesis:1989-76849
Copyright: Copyright of this thesis is held by the author.
Date Deposited: 14 Jan 2020 09:32
Last Modified: 14 Jan 2020 09:32

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