Antibody Studies with DNA Methylase

McGarvey, Margaret (1989) Antibody Studies with DNA Methylase. MSc(R) thesis, University of Glasgow.

Abstract

DNA methylase catalyses the transfer of a methyl group from S-Adenosyl-L-Methionine to the 5 position on deoxycytidine residues in CpG dinucleotides of DNA. DNA methylase has been purified 2000 fold from mouse Krebs II ascites tumour cells by modification of the original purification procedure of Turnbull and Adams (1976). The purified enzyme has been used to raise polyclonal antibodies in rabbits in order to study the enzyme in vitro.

• Item Type: Thesis (MSc(R))
• Qualification Level: Masters
• Keywords: Biochemistry
• Date of Award: 1989
• Depositing User: Enlighten Team
• Unique ID: glathesis:1989-76855
• Copyright: Copyright of this thesis is held by the author.
• Date Deposited: 14 Jan 2020 11:53
• Last Modified: 14 Jan 2020 11:53
• URI: https://theses.gla.ac.uk/id/eprint/76855