The Construction of a Monoclonal Diagnostic System for the Field Detection of V. cholerae

Al-Riyami, Asya Ali Masoud (1989) The Construction of a Monoclonal Diagnostic System for the Field Detection of V. cholerae. PhD thesis, University of Glasgow.

Abstract

Cholera is an acute diarrheal disease that is characterized by massive loss of fluids and electrolytes. If it remains untreated, in its most severe form it may result in death. The causative agent is Vibrio cholerae, which was first described by Robert Koch (1884). The disease is contracted by the ingestion of water or food contaminated by the excreta of persons harbouring the bacilli. Since it is exquisitely sensitive to gastric acid, at least 100 million vibrios are required for infection in a reasonably healthy person, but in a malnourished victim or someone with no gastric acidity, 10,000 to 1 million vibrios can produce disease. The human is the only host of V. cholerae (Smith, 1985).

• Item Type: Thesis (PhD)
• Qualification Level: Doctoral
• Keywords: Biochemistry, Bioengineering, Microbiology
• Date of Award: 1989
• Depositing User: Enlighten Team
• Unique ID: glathesis:1989-76895
• Copyright: Copyright of this thesis is held by the author.
• Date Deposited: 14 Jan 2020 09:29
• Last Modified: 14 Jan 2020 09:29
• URI: https://theses.gla.ac.uk/id/eprint/76895