Phospholipid Signalling Pathways in ras Transformed Fibroblasts

Black, Fiona Marian (1990) Phospholipid Signalling Pathways in ras Transformed Fibroblasts. PhD thesis, University of Glasgow.

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The aim of the work described in this thesis was to investigate the effects of over-expression of normal ras proteins upon lipid signalling pathways in cultured NIH-3T3 fibroblasts. The ras oncogene family has been implicated in the growth and development of a high percentage of human tumours, but despite extensive research the mechanism of action of ras is still unknown. It has been proposed that p2 proteins function in a G-protein-like manner mediating the effects of certain growth factors, by coupling their receptors to the stimulation of PIC.

Item Type: Thesis (PhD)
Qualification Level: Doctoral
Keywords: Molecular biology, Physiology
Date of Award: 1990
Depositing User: Enlighten Team
Unique ID: glathesis:1990-76971
Copyright: Copyright of this thesis is held by the author.
Date Deposited: 14 Jan 2020 09:25
Last Modified: 14 Jan 2020 09:25

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