Studies of the Relationship Between mRNA Stability and Gene Function in Saccharomyces cerevisiae

Moore, Joyce (1991) Studies of the Relationship Between mRNA Stability and Gene Function in Saccharomyces cerevisiae. PhD thesis, University of Glasgow.

Abstract

Twelve S. cerevisiae cDNAs, characterised by Santiago (1986) on the basis of the half-lifes of the respective mRNAs, have been partially or completely sequenced. To four have been assigned a definite function. cDNA10, which generates a long half-life mRNA, encodes the glucose-inducible form of the glycolytic enzyme, enolase. cDNAs 90, 39 and 13, each of which generates a short half-life mRNA, encode ribosomal proteins L3, L29 and YL6 respectively. cDNA46, which generates a long half-life mRNA, is related to a mouse gene of unknown function, MER5. In addition, there is circumstantial evidence that among the unidentified cDNAs that generate short half-life mRNAs are several that encode ribosomal proteins.

• Item Type: Thesis (PhD)
• Qualification Level: Doctoral
• Keywords: Genetics
• Date of Award: 1991
• Depositing User: Enlighten Team
• Unique ID: glathesis:1991-77041
• Copyright: Copyright of this thesis is held by the author.
• Date Deposited: 14 Jan 2020 09:22
• Last Modified: 14 Jan 2020 09:22
• URI: http://theses.gla.ac.uk/id/eprint/77041