Clinical and theoretical studies with the opioid analgesic fentanyl

Higgins, Michael Joseph (1990) Clinical and theoretical studies with the opioid analgesic fentanyl. MSc(R) thesis, University of Glasgow.

Abstract

This thesis concerns two investigations into the opioid analgesic fentanyl. The first is a clinical investigation into the safety and efficacy of fentanyl administered by inhalation. The second is a theoretical assessment of the feasibility and merits of applying an alternative form of pharmacokinetic model to the drug. The second project is linked chronologically and conceptually to the first in that it grew out of a general interest in the pharmacology of fentanyl developed during the first study and in that it provides a useful theoretical framework for considering the comparative pharmacokinetics of drug delivered intravenously and drug delivered for absorbtion from other sites. The thesis is in two related but essentially self-contained parts preceded by a brief review of fentanyl pharmacology.

• Item Type: Thesis (MSc(R))
• Qualification Level: Masters
• Subjects: R Medicine > RS Pharmacy and materia medica
• Colleges/Schools: College of Medical Veterinary and Life Sciences
• Supervisor's Name: Asbury, Dr. A.J.
• Date of Award: 1990
• Depositing User: Enlighten Team
• Unique ID: glathesis:1990-77046
• Copyright: Copyright of this thesis is held by the author.
• Date Deposited: 14 Jan 2020 09:22
• Last Modified: 02 Aug 2023 11:39
• Thesis DOI: 10.5525/gla.thesis.77046
• URI: http://theses.gla.ac.uk/id/eprint/77046