A Study of the Inter-Relationships Between Ketosis and Leucine, Alanine and Glucose Metabolism in Normal and Obese Fasted Human Subjects Using Tracer Methodology

Scobie, Ian Neilson (1987) A Study of the Inter-Relationships Between Ketosis and Leucine, Alanine and Glucose Metabolism in Normal and Obese Fasted Human Subjects Using Tracer Methodology. MD thesis, University of Glasgow.

Abstract

1. This thesis describes a quantitative investigation of leucine, alanine and glucose turnover, metabolite concentrations and hormone levels (insulin, C-peptide, cortisol and glucagon) in normal weight subjects studied after 12 hours and 60 hours of starvation and in obese subjects studied after 12 hours, 60 hours and 2 weeks of starvation. Leucine turnover was measured with L-[1-14C] leucine, alanine turnover with L-[1-14C] alanine and glucose turnover with D-[3-3H] glucose.

• Item Type: Thesis (MD)
• Qualification Level: Doctoral
• Keywords: Medicine, Physiology, Endocrinology
• Date of Award: 1987
• Depositing User: Enlighten Team
• Unique ID: glathesis:1987-77262
• Copyright: Copyright of this thesis is held by the author.
• Date Deposited: 14 Jan 2020 09:14
• Last Modified: 14 Jan 2020 09:14
• URI: https://theses.gla.ac.uk/id/eprint/77262