Asymmetric synthesis of beta-lactams

Brown, Alan Daniel (1990) Asymmetric synthesis of beta-lactams. PhD thesis, University of Glasgow.

Abstract

Several routes to optically enriched 2-azetidinones have been investigated. The most successful of these was that based on highly diastereoselective cycloaddition reactions between homochiral imines derived from (S)-methyl lactate and a range of achiral ketenes. The synthetic potential of the resulting azetidinones with respect to bicyclic beta-lactam formation has also been investigated.

• Item Type: Thesis (PhD)
• Qualification Level: Doctoral
• Keywords: Organic chemistry
• Date of Award: 1990
• Depositing User: Enlighten Team
• Unique ID: glathesis:1990-78158
• Copyright: Copyright of this thesis is held by the author.
• Date Deposited: 28 Feb 2020 12:09
• Last Modified: 28 Feb 2020 12:09
• URI: https://theses.gla.ac.uk/id/eprint/78158