Synthetic Studies in the Trichothecane Field

Malchenko, Swiatoslaw (1972) Synthetic Studies in the Trichothecane Field. PhD thesis, University of Glasgow.

Abstract

Two synthetic routes towards 3,6-dimethyl-8-oxo-9-oxa-bicyclo[4,3,0]non-2-ene , a crucial intermediate in the synthesis of the sesquiterpenoid mould metabolite trichodermin, are discussed. The strategy and ultimate approach towards the most widely distributed sesquiterpenoid component of the tricho-thecanes, verrucarol, via 3-methyl-6-hydroxymethyl-8-oxo-9-oxabicyclo[4,3,0]non-2-ene,are fully described.

• Item Type: Thesis (PhD)
• Qualification Level: Doctoral
• Keywords: Organic chemistry
• Date of Award: 1972
• Depositing User: Enlighten Team
• Unique ID: glathesis:1972-78600
• Copyright: Copyright of this thesis is held by the author.
• Date Deposited: 28 Feb 2020 12:09
• Last Modified: 28 Feb 2020 12:09
• URI: https://theses.gla.ac.uk/id/eprint/78600