Ellis, Drummond
(1949)
Part I. Experiments in the Colchicine Series. Part II. Studies in the Synthesis of Diazacarbazoles.
PhD thesis, University of Glasgow.
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Abstract
The synthesis of a substance related in structure to colchicine has been completed. The new compound proved to be different from a degradation product of the alkaloid, with which it was isomeric. This observation has a bearing on the structure of colchicine. A preliminary report shows that the substance synthesised inhibits cell-mitosis: a re-evaluation of the structural factors essential for biological activity in this type of substance is consequently regarded as necessary.
| Item Type: |
Thesis
(PhD)
|
| Qualification Level: |
Doctoral |
| Keywords: |
Organic chemistry |
| Date of Award: |
1949 |
| Depositing User: |
Enlighten Team
|
| Unique ID: |
glathesis:1949-79732 |
| Copyright: |
Copyright of this thesis is held by the author. |
| Date Deposited: |
31 Mar 2020 09:09 |
| Last Modified: |
31 Mar 2020 09:09 |
| URI: |
http://theses.gla.ac.uk/id/eprint/79732 |
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