Cardiac Infarction: A Study of 125 Cases

Wright, Joseph Houston (1932) Cardiac Infarction: A Study of 125 Cases. MD thesis, University of Glasgow.

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The study of coronary occlusion is comparatively young and the tempering of experience is still necessary. I have endeavoured to summarize the main clinical features by the typical case and to describe the unusual features which may be encountered. I have classified the cases in various groups according to their main outstanding clinical features and their ultimate prognosis. I have found that previous classifications do not suffice and no doubt with further experience the present classification will also be incomplete. My results are in the main confirmatory but I feel they will serve as a necessary link between the apparently divergent views of others.The sequential alterations of the electrocardiogram in coronary occlusions have been established. Daily electrocardiography in certain of my cases has enabled me to record these frequent variations and I have described the sequence usually encountered. I have met with most types of electrocardiographic abnormality during the course of this study and I have attempted to classify these according to their importance. On three occasions, where single tracings were obtained, I found no abnormality of the electrocardiogram. I place less importance on this than I should have done two or three years ago. Changes may be slow in one case, rapid in another and without several tracings it is unwise to assume that they did not or will not occur. Finally I have studied the question of relationship between electrocardiographic abnormality and the site of the cardiac infarction. My opportunities for such a study have been exceptional. The post mortem lesions were investigated in seventeen cases in which previous electrocardiographic tracings were obtained. This number exceeds that of any previous publications. Most of the pathological lesions secondary to coronary occlusion were encountered and the electrocardiographic changes were many and varied. I feel that I have sufficient data to establish the fact that certain of the changes of the electrocardiogram are dependent on the site of the cardiac infarction.

Item Type: Thesis (MD)
Qualification Level: Doctoral
Keywords: Medicine
Date of Award: 1932
Depositing User: Enlighten Team
Unique ID: glathesis:1932-79940
Copyright: Copyright of this thesis is held by the author.
Date Deposited: 31 Mar 2020 09:09
Last Modified: 31 Mar 2020 09:09

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