An Experimental Investigation of the Effects of Trauma to the Central Nervous System

Clark, Alfred Mackenzie (1934) An Experimental Investigation of the Effects of Trauma to the Central Nervous System. PhD thesis, University of Glasgow.

Abstract

This investigation was undertaken with a view of determining the nature of the "Shock," which is associated with trauma to the Central Nervous System. It deals with the effect of trauma to the Central Nervous System as opposed to the effects of trauma on the Central Nervous System, and the experiments performed have been confined mainly to the brain. In this investigation I have attempted to find out whether the shock to the Central Nervous System is of nervous origin, or if there be a chemical factor present, or if it be a combination of both factors. It is well known, that operations on the Central Nervous System are accompanied by a fall of blood pressure, which may be marked, but that usually the blood pressure will recover if the operation be stopped; and a patient after a severe head injury is in a shocked condition. I have divided this investigation into two main parts, the first dealing with trauma produced under various experimental conditions and also with the effects of intracranial pressure, and the second dealing with the question of the presence in the brain of a chemical substance or substances, which may cause a fall of blood pressure and produce shock.

• Item Type: Thesis (PhD)
• Qualification Level: Doctoral
• Keywords: Medicine, Neurosciences
• Date of Award: 1934
• Depositing User: Enlighten Team
• Unique ID: glathesis:1934-79961
• Copyright: Copyright of this thesis is held by the author.
• Date Deposited: 03 Mar 2020 10:16
• Last Modified: 03 Mar 2020 10:16
• URI: https://theses.gla.ac.uk/id/eprint/79961