Ramsey, Ian Keith
(1993)
Recombinant Surface Glycoproteins of Feline Leukaemia Virus.
PhD thesis, University of Glasgow.
Full text available as:
Abstract
Feline leukaemia virus (FeLV) is a major cause of degenerative and proliferative diseases of myeloid, lymphoid and erythroid origin in domestic cats. The envelope of FeLV, which is a typical retrovirus, is studded with a transmembrane protein (TM) that anchors an external surface glycoprotein (SU). The FeLV SU (gp70) carries both neutralising epitopes and subgroup phenotypic determinants. FeLV occurs naturally in 3 subgroups, which are defined by a superinfection interference assay, suggesting that three FeLV cellular receptors exist, one for each subgroup. The regions of SU which determine the A/C phenotype have been defined as lying in a small variable region towards the amino terminus of the protein.
| Item Type: |
Thesis
(PhD)
|
| Qualification Level: |
Doctoral |
| Additional Information: |
Adviser: Oswald Jarrett |
| Keywords: |
Virology, Veterinary science |
| Date of Award: |
1993 |
| Depositing User: |
Enlighten Team
|
| Unique ID: |
glathesis:1993-74565 |
| Copyright: |
Copyright of this thesis is held by the author. |
| Date Deposited: |
13 Nov 2019 15:58 |
| Last Modified: |
13 Nov 2019 15:58 |
| URI: |
http://theses.gla.ac.uk/id/eprint/74565 |
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