Role of Nitric Oxide and Prostacyclin in Modulating Pulmonary Vascular Tone

Elbishti, Wisam (1995) Role of Nitric Oxide and Prostacyclin in Modulating Pulmonary Vascular Tone. PhD thesis, University of Glasgow.

Abstract

The aim of this study was to investigate the possible role of the endothelium-derived vasorelaxant factors, NO and prostacyclin, in the maintenance of the low pulmonary vascular tone. This was achieved by investigating whether a basal release of NO and prostacyclin is involved in modulating the responsiveness of isolated pulmonary arteries to vasoconstrictors, and by examining the ability of various humoral agents to stimulate NO release in this vascular bed. The extent to which this basal and stimulated release correlates with artery size was also investigated. (Abstract shortened by ProQuest.).

• Item Type: Thesis (PhD)
• Qualification Level: Doctoral
• Additional Information: Adviser: David Pollock
• Keywords: Medicine, Pharmacology
• Date of Award: 1995
• Depositing User: Enlighten Team
• Unique ID: glathesis:1995-75464
• Copyright: Copyright of this thesis is held by the author.
• Date Deposited: 19 Nov 2019 20:02
• Last Modified: 19 Nov 2019 20:02
• URI: https://theses.gla.ac.uk/id/eprint/75464