Blunt, Gillian
(2002)
Developing Novel Synthetic Methods for the Pauson-Khand Reaction.
PhD thesis, University of Glasgow.
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Abstract
The Pauson-Khand cyclisation is one of the most useful reactions for the formation of cyclopentenone ring systems. It is a [2 + 2 + 1] cycloaddition between an alkyne, alkene and one molecule of carbon monoxide. The reaction is mediated by dicobalt octacarbonyl. The aim was to develop a general and simple route to generating cyclopentenone ring systems utilising the Pauson-Khand cyclisation. We chose to use amines as promoters as opposed to the more commonly used amine N-oxides. An efficient route to cyclopentenone i was developed. Substrate ii was heated to 50
| Item Type: |
Thesis
(PhD)
|
| Qualification Level: |
Doctoral |
| Additional Information: |
Adviser: Jennifer Matthews |
| Keywords: |
Organic chemistry |
| Date of Award: |
2002 |
| Depositing User: |
Enlighten Team
|
| Unique ID: |
glathesis:2002-76215 |
| Copyright: |
Copyright of this thesis is held by the author. |
| Date Deposited: |
19 Nov 2019 16:28 |
| Last Modified: |
19 Nov 2019 16:28 |
| URI: |
http://theses.gla.ac.uk/id/eprint/76215 |
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