Studies on the mode of action of reserpine

Gillis, Charles N (1958) Studies on the mode of action of reserpine. PhD thesis, University of Glasgow.

Abstract

1. The actions of reserpine have been investigated using a number of tissues containing contractile elements. 2. Both the direct effects of reserpine and its actions upon drug- induced responses have been investigated. 3. Reserpine has been found to antagonise some of the effects of acetylcholine, (-)-adrenaline, (-)-noradrenaline, 5-hydroxytryptamine, pitressin, barium chloride and potassium chloride on such preparations as the frog rectus abdominis muscle, the isolated guinea-pig ileum, and auricles, the isolated perfused heart and the spinal cat. 4. It is suggested that reserpine may affect the metabolic processes which underlie muscular contraction.

• Item Type: Thesis (PhD)
• Qualification Level: Doctoral
• Additional Information: Adviser: Stantley Alstead
• Keywords: Pharmacology
• Date of Award: 1958
• Depositing User: Enlighten Team
• Unique ID: glathesis:1958-72562
• Copyright: Copyright of this thesis is held by the author.
• Date Deposited: 11 Jun 2019 11:06
• Last Modified: 11 Jun 2019 11:06
• URI: https://theses.gla.ac.uk/id/eprint/72562