A Stereochemical Study of the SE' Reaction

Duffin, Raymond Joseph (1981) A Stereochemical Study of the SE' Reaction. PhD thesis, University of Glasgow.

Abstract

The in vivo isomerisation of iso-pentenyl pyrophosphate (13) to dimethylallyl pyrophosphate (14) and the condensation of these two C-5 units to geranyl pyrophosphate (15), although formally recognisable as SE2 processes (Scheme 9) have been rationalised in a stepwise manner.One reason for doing so is the uncertainty as to the stereochemical preference in the non-enzymic SE reaction and this is compounded by the fact that of the two biological reactions, one proceeds with overall syn- and the other with overall anti-stereochemistry.

• Item Type: Thesis (PhD)
• Qualification Level: Doctoral
• Keywords: Organic chemistry
• Date of Award: 1981
• Depositing User: Enlighten Team
• Unique ID: glathesis:1981-77166
• Copyright: Copyright of this thesis is held by the author.
• Date Deposited: 14 Jan 2020 09:17
• Last Modified: 14 Jan 2020 09:17
• URI: https://theses.gla.ac.uk/id/eprint/77166