The Effects of Drugs on Conduction and Transmission in Autonomically-Innervated Smooth Muscle

Beattie, David Thomas (1987) The Effects of Drugs on Conduction and Transmission in Autonomically-Innervated Smooth Muscle. PhD thesis, University of Glasgow.

Abstract

1. The prejunctional actions of a number of Ca 2+ channel antagonists were investigated. Their effects were assessed on both nerve action potential (AP) conduction and neuromuscular transmission in the vas deferens and internal anal sphincter (i.a.s.) of the guinea-pig and in the rat anococcygeus. Nerve APs were recorded extracellularly with a suction electrode and transmitter release measured by intracellular electrical recording of smooth muscle junction potentials and analysis of the overflow of radiolabelled transmitter.

• Item Type: Thesis (PhD)
• Qualification Level: Doctoral
• Keywords: Pharmacology
• Date of Award: 1987
• Depositing User: Enlighten Team
• Unique ID: glathesis:1987-77453
• Copyright: Copyright of this thesis is held by the author.
• Date Deposited: 14 Jan 2020 09:08
• Last Modified: 14 Jan 2020 09:08
• URI: https://theses.gla.ac.uk/id/eprint/77453